Search Results

Showing results 1-10 of 61 for 'genetics'

  • Yizhar, Oren_lab
    Lighting Up the Mechanisms of Brain Disease

    In Issue No. 47 of Weizmann Views, serendipity leads Dr. Ofer Yizhar to his life’s work: pioneering the remarkable new field of optogenetics. Optogenetics combines optics – the branch of physics concerned with light – and genetics to offer previously unimaginable new ways of studying the brain. Dr. Yizhar's work has particular import for the understanding of autism.

  • Globes Neuroquest
    NeuroSense to Develop ALS Treatment

    Prof. Eran Hornstein discovered that a small molecule already on the market for a different disease can also be active in treating ALS. As Globes reports, NeuroSense Therapeutics will develop the technology; since ALS is considered a priority, NeuroSense believes that it will be able to bring the drug to market within five years.

  • isef-suchowski__isef
    Gene Analysis Adds Layers to Understanding How Our Livers Function

    Our livers perform a host of vital functions, including clearing our bodies of toxins and producing most of the carrier proteins in our blood. Weizmann researchers have now shown that the liver’s amazing multitasking capacity is due at least in part to a clever division of labor among its cells. In fact, they say, “We’ve found that liver cells can be divided into at least nine different types, each specializing in its own tasks.”

  • February is American Heart Month

    Our hearts mean many things: love, strength, loyalty. But even if we look at hearts from a purely biological perspective, they are still awesome – and complicated, particularly when it comes to disease. That’s why, for American Heart Month, we’d like to share some of the many approaches Weizmann Institute scientists are taking to fight heart disease.

  • Gene Editing Takes on New Roles

    Two new and powerful research methods – CRISPR gene editing and single-cell genomic profiling – have now been combined to produce a tool fine enough to enable scientists to observe life’s most nuanced processes. Prof. Ido Amit and his lab have so refined CRISPR that scientists can understand biological processes in shades of grey – not just black and white.

  • One Patent, Three Drugs

    Many years ago, Prof. Michael Sela and colleagues found that antibodies inhibiting EGFR, a receptor that plays a role in cancer, have a synergistic anti-cancer effect when used with chemotherapy. That discovery has now led to three cancer-treating drugs: Erbitux®, Vectibix®, and, most recently, Portrazza, just FDA approved for a form of lung cancer.

  • Using Basic Science to Advance Cancer Research

    Prof. Moshe Oren has spent decades studying the p53 gene, which plays a key role in keeping healthy cells from turning cancerous. His basic research has inspired other scientists to build on his findings, potentially leading to p53-based cancer treatments. As head of the Moross Integrated Cancer Center, Prof. Oren’s knowledge will be more valuable than ever.

  • Preventing Cancer: The Weizmann Institute's Moross Integrated Cancer Center

    The Weizmann Institute of Science’s Moross Integrated Cancer Center (MICC) aims to revolutionize cancer prevention, detection, and treatments. Several of the senior scientists involved with the MICC – Prof. Zvi Livneh, Prof. Moshe Oren, Dr. Tamar Paz-Elizur, Dr. Eran Elinav, and Dr. Ayelet Erez – discuss directions in cancer prevention research.

  • Natural Metabolite Might Reset Aging Biological Clocks

    As we age, our biological clocks wind down – but why? Dr. Gad Asher, who studies circadian clocks – genetic mechanisms that keep us in tune with cycles of day and night – has identified a link between the clocks and a group of metabolites called polyamines. Found in many foods, polyamines could fight aging – as they did in Dr. Asher’s mice.

  • These Foods Speed Up Circadian Rhythm And Increase Lifespan

    As we age, our biological clocks wind down – but why? Weizmann’s Dr. Gad Asher has found a link between the clocks and a group of metabolites called polyamines. Found in many foods, polyamines could help us fight aging. reports on the research and a polyamine-laden diet, including soybeans, corn, green peas, blue cheese.