“We don’t just want to find the genes involved in cancer,” says Prof. Yardena Samuels, of the Weizmann Institute of Science’s Department of Molecular Cell Biology, “we want to understand what those genes do. We want to reveal the complete picture of a cancer genome.” That is something of a tall order, considering that cells from melanoma, the cancer Prof. Samuels is researching, can contain anywhere from tens to thousands of mutations. On average, melanoma – the deadliest form of skin cancer – has more mutations in the DNA of its cells than any other solid tumor. Among other things, this range of mutations explains why a recent treatment designed to target melanoma will only help around 50% of those with the disease, despite representing a large step forward.
What would we be without our brains? They hold our memories, our sense of humor, our ability to do math in our heads or dance or cook, to know all the world’s capitols or cite Shakespeare – they make us us.
As the number of older people in the world continues to rise, so do brain diseases such as Alzheimer’s – and no one wants to lose the essence of who they are.
Fortunately, Weizmann Institute scientists have been working to strengthen the mechanisms that promote healthy aging and find new and better ways of treating disease once it occurs.
May is Melanoma/Skin Cancer Detection and Prevention Month: the perfect time to learn more about the disease – and what the Weizmann Institute of Science is doing to help.
Did you know that skin cancer is the most common cancer in America? And that it’s been on the rise for more than 30 years?
The single most significant cause of skin cancer is the sun. That’s certainly true when it comes to melanoma – the deadliest of all skin cancers – with the Skin Cancer Foundation citing research that shows that 86% of melanomas are linked to UV radiation. Thus, prevention – such as wearing a high-SPF sunblock or protective clothing anytime we go outside, even on overcast days – and early screening are the most important tools in our skin-cancer-defeating arsenal.
On April 11, 2018, American Committee supporters from across the country heard from CEO Marshall S. Levin during his most recent conference call focused on “Science at the Leading Edge: Latest Breakthroughs from the Weizmann Institute of Science.”
Prof. Avishay Gal-Yam searches the skies for exploding stars that contain the elements necessary for life, and is working with NASA and others on a UV-wavelength satellite.
In just the past few years, understanding of the microbiome has transformed how we perceive diet and nutrition, and is already altering how we take care of ourselves. Weizmann Institute scientists from a range of disciplines – just some of which are immunology, neuroscience, biology, genetics, chemistry, machine learning, mathematics, and computer science – have led the way in microbiome research, regularly producing headline-making discoveries. Several of these researchers are also medical doctors, and their experience in working with patients helps move therapies more quickly from the lab to you.
The good news is that we’re living longer than ever. The not-so-good news is that age-related diseases – including vision problems – are also sticking around. As just one example, the National Institutes of Health says that because of increased longevity, the number of people with age-related macular degeneration, or AMD, grew 18 percent – from 1.75 to 2.07 million – over a single decade.
Fortunately, the Weizmann Institute of Science’s dedicated researchers are investigating age-related diseases from a number of angles, from the basic biochemistry of the retina to imaging the brain in action. Interdisciplinary groups study computer-aided and artificial vision and experiment with vaccines that could prevent degenerative eye diseases. By finding ways to better understand, protect, preserve, and treat the eyes, Weizmann scientists are improving life for people worldwide.
Prof. Karina Yaniv was first in the world to grow lymph cells in the lab, and is working to develop clinical treatments for conditions such as lymphedema.
As we look forward to another year of innovative, life-improving science for the benefit of humanity, what better place to find hope for the future than in young scientists?
The Weizmann Institute of Science scours the globe for the brightest, most talented researchers, always aiming to bring fresh ideas and creative thinkers to campus. We’d like you to meet a few of these remarkable new recruits:
©2019 American Committee for the Weizmann Institute of Science
