Advancing Technology

The Genomics Revolution: The Importance of Next-Gen Instrumentation

In this video, Prof. Doron Lancet, Head of the Crown Human Genome Center at the Weizmann Institute, and Dr. Daniela Amann-Zalcenstein, Head of High-Throughput Sequencing, explain the importance of new next-generation high-throughput sequencing technology. Prof. Lancet thanks Chicago’s Crown family for allowing the Institute to “start the game,” and the American Committee’s New York Region “for allowing us to complete the process.”

The purchase of such equipment is a major expenditure – however, as Prof. Lancet states, the next-gen technology enables the scientists to move from “mega sequencing” to “giga-sequencing.” And as Dr. Amann-Zalcenstein says, because the technology lets ​scientists move from looking at individual genes to studying the entire genome, it enables research that is “much less hypothesis-based” than today’s.

Investigations utilizing next-generation instrumentation for genomics research is expected to lead to major biomedical advances, such as the discovery of new disease-related genes, thus helping develop new and improved cures; however, as Prof. Lancet points out, it can sequence the genomes of anything, from plants to mice to humans.