About Us
Founded in 1944, the American Committee for the Weizmann Institute of Science develops philanthropic support for the Weizmann Institute in Israel, and advances its mission of science for the benefit of humanity.
Mar 09, 2020...
Electrons spin. It's a fundamental part of their existence. Some spin “up” while others spin “down.” Scientists have known this for about a century, thanks to quantum physics.
They've also known that magnetic fields can affect the direction of an electron’s quantum spin, flipping it from up to down and vice versa. And it doesn't take much: Even a bacterial cell can do it.
Researchers at USC Dornsife College of Letters, Arts and Sciences and Israel's Weizmann Institute of Science have found that protein “wires” connecting a bacterial cell to a solid surface tend to transmit electrons with a particular spin.
Apr 06, 2020...
A comprehensive review of published studies on gut microbiota, immunity and arthritis suggests that having a microbial imbalance may precede the development of spondyloarthritides and osteoarthritis.
The review, which was published in Seminars in Arthritis and Rheumatism, suggests a close connection between an impaired microbiota, the immune system and inflammatory arthritis.
“In this review, we presented data supporting the idea that dysbiosis via a close, dynamic and tightly regulated cross talk with gut-associated lymphoid tissue, governs the development of inflammatory arthropathies, such as rheumatoid arthritis, spondyloarthritis and osteoarthritis. It became clear that unfavorable dysbiosis-mediated immune alterations precede the development of these disorders suggesting causal relationships in this link,” wrote authors Alexander Kalinkovich of the Weizmann Institute of Science in Israel, and Gregory Livshits of Tel Aviv University.
https://www.weizmann-usa.org/news-media/news-releases/the-self-synthesizing-ribosome/
Apr 20, 2020... REHOVOT, ISRAEL—April 20, 2020—As the cell’s protein factory, the ribosome is the only natural machine that manufactures its own parts. That’s why understanding how the machine itself is made could unlock the door to everything from understanding how life develops to designing new methods of drug production. An intensive research effort at the Weizmann Institute of Science has now demonstrated the self-synthesis and assembly of the small subunit of a ribosome – 30S – on a surface of a chip. The findings were published in Science Advances.
Jun 02, 2020... REHOVOT, ISRAEL—June 2, 2020—Cancer cells are comfy havens for bacteria. That conclusion arises from a rigorous study of over 1,000 tumor samples of different human cancers. The study, headed by researchers at the Weizmann Institute of Science, found bacteria living inside the cells of all the cancer types – from brain to bone to breast cancer – and even identified unique populations of bacteria residing in each type of cancer. The research suggests that understanding the relationship between a cancer cell and its “mini-microbiome” may help predict the potential effectiveness of certain treatments or may point, in the future, to ways of manipulating those bacteria to enhance the actions of anticancer treatments. The findings of this study were published in Science and featured on the cover.
May 28, 2020...
The first comprehensive survey of the microorganisms that live inside tumours has found that bacteria reside in those from many different cancer types, but it is unclear whether they contribute to tumour growth.
These bacteria make up part of a tumour’s microbiome – the complex community of bacteria, fungi and other microbes that live inside it.
Bacteria have previously been found in tumours in the bowel and other tissues in the body that are routinely exposed to microbes. However, less is known about their presence in tumours from other cancers, like those of the bone, brain and ovary.
Jul 20, 2020... REHOVOT, ISRAEL—July 20, 2020—Scientists searching for better diagnostic tests, drugs, or vaccines against a virus must begin by deciphering the structure of that virus. And when the virus in question is highly pathogenic, such research can be quite dangerous. Prof. Roy Bar-Ziv of the Weizmann Institute’s Department of Materials and Interfaces; staff scientist Dr. Shirley Shulman Daube; Dr. Ohad Vonshak, a former research student in the Bar-Ziv lab; and current research student Yiftach Divon have an original solution to this obstacle. They demonstrated the production of viral parts within artificial cells.
Sep 16, 2020... REHOVOT, ISRAEL—September 16, 2020—By tracking the evolution of what may be our oldest means of fighting off viral infection, a group at the Weizmann Institute of Science has uncovered a gold mine of antiviral substances that may lead to the development of highly effective antiviral drugs. These substances are made by virus-fighting enzymes known as viperins, which were previously known to exist only in mammals and have now been found in bacteria. The molecules produced by the bacterial viperins are currently undergoing testing against human viruses such as influenza and COVID-19. The study was published in Nature.
Sep 17, 2020...
Virus-fighting enzymes, known as viperins, which have been previously thought to exist only in mammals, have been also detected in bacteria and are being tried against human viruses, including the coronavirus, according to a new study led by a team of researchers from the Weizmann Institute of Science, which was published in the leading scientific magazine Nature.
The team, led by Professor Rotem Sorek from the Molecular Genetics Department in the institute, discovered that bacteria produce a large variety of antiviral substances that have the potential to help fighting viral diseases.
https://www.weizmann-usa.org/news-media/in-the-news/the-coronavirus-unveiled/
Oct 09, 2020...
In February, as the new coronavirus swept across China and shut down entire cities, a scientist named Sai Li set out to paint its portrait.
At the time, the best pictures anyone had managed to take were low-resolution images, in which the virus looked like a barely discernible smudge.
Dr. Li, a structural biologist at Tsinghua University in Beijing, joined forces with virologists who were rearing the virus in a biosafety lab in the city of Hangzhou. Those researchers doused the viruses with chemicals to render them harmless and then sent them to Dr. Li.
Nov 05, 2020... REHOVOT, ISRAEL—November 5, 2020—Peculiar hybrid structures called retrons that are half RNA, half single-strand DNA are found in many species of bacteria. Since their discovery around 35 years ago, researchers have learned how to use retrons for producing single strands of DNA in the lab – yet despite extensive research into the matter, the retrons’ function in the bacteria was unknown. Now, in a paper published in Cell, Weizmann Institute of Science researchers report that the longstanding mystery has been solved: Retrons are immune system “guards” that ensure the survival of the bacterial colony when it is infected by viruses.
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