About Us
Founded in 1944, the American Committee for the Weizmann Institute of Science develops philanthropic support for the Weizmann Institute in Israel, and advances its mission of science for the benefit of humanity.
Mar 04, 2019...
Lymphoid organs in the small intestines. Red: B cells aggregated in the “training centers.” Green: cells with the ability to secrete effective antibodies exiting the centers for the intestinal tissue
REHOVOT, ISRAEL—March 4, 2019—Only a few vaccines – for example, polio and rotavirus – can be given orally. Most must be delivered by injection. Weizmann Institute of Science researchers suggest this may be, in part, because the “training program” of the immune cells in the gut takes place under harsh conditions. Using a novel imaging method that captures all of the immune cells’ niches within a single organ, Dr. Ziv Shulman and research student Adi Biram investigated the training process for the gut-based cells involved in long-term immunity. Their findings, published in Nature Immunology, provide new insights that may, in the future, lead to the design of more effective oral vaccines.
Jul 23, 2019...
Image by Tashatuvango via Shutterstock.com
A trailblazing study by Israeli researchers suggests that intestinal microbes may have a direct effect on the course of amyotrophic lateral sclerosis (ALS), the incurable, fatal neurodegenerative disease also known as Lou Gehrig’s disease that affected physicist Stephen Hawking.
Published today in Nature, the study by researchers at the Weizmann Institute of Science revealed that the progression of an ALS-like disease in lab mice was slowed after the mice received certain strains of gut microbes or substances known to be secreted by these microbes.
https://www.weizmann-usa.org/news-media/news-releases/gut-microbes-may-affect-the-course-of-als/
Jul 22, 2019...
Gut microbes such as these were found to have altered levels in ALS patients
REHOVOT, ISRAEL—July 22, 2019—Researchers at the Weizmann Institute of Science have shown in mice that intestinal microbes, collectively termed the gut microbiome, may affect the course of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease. As reported in Nature, progression of an ALS-like disease was slowed after the mice received certain strains of gut microbes or substances known to be secreted by these microbes. Preliminary results suggest that the findings on the regulatory function of the microbiome may be applicable to human patients with ALS.
Jul 22, 2019...
When immune cells (macrophage, blue) meet bacteria (red), the first day or two is critical for the eventual outcome
REHOVOT, ISRAEL—July 22, 2019—First impressions are important – they can set the stage for the entire course of a relationship. The same is true for the impressions the cells of our immune system form when they first meet a new bacterium. Using this insight, Weizmann Institute of Science researchers have developed an algorithm that may predict the onset of diseases such as tuberculosis. The findings of this research were published in Nature Communications.
Jul 25, 2019...
BiondVax
A universal flu vaccine is the key to combating the ever-mutating flu virus, but did we ever really stop to think about whether there is a better way?
The flu virus, or influenza, is far more than a week-long inconvenience that pulls us away from our commitments, although that, in and of itself, is pretty annoying. The flu can get deadly fast. According to the World Health Organization, influenza kills up to 650,000 people each year. Read that number again. In the US alone, the flu kills about 12,000 people in mild years, and up to 56,000 people in the more severe years, according to the Center for Disease Control.
Nov 18, 2019...
The idea of ‘gut health’ barely existed a few years ago, but now, people in the UK spend around £750 million every year on probiotic products — ‘beneficial’ bacteria which is supposed to boost our health.
People take probiotics believing they increase levels of beneficial bacteria and will boost their immune system, digestion, mental health and more.
But last week, an expert warned that fermented foods such as sauerkraut — often consumed because of their probiotic effect — may trigger bloating, headaches and allergies.
Mar 09, 2020...
JERUSALEM, Feb. 24 (Xinhua)— Israeli scientists found that short-term acute inflammation in the mother's body during pregnancy can cause autism to the embryo, said Weizmann Institute of Science (WIS) in central Israel on Monday.
Signs of autism usually appear around two or three years old, but it is considered a neurodevelopmental disease, which suggests that changes could already be “brewing” in the embryonic brain.
Apr 17, 2019...
For many years, scientists believed that the brain was completely isolated from the immune system because of a shield called the blood-brain barrier.
That dogma has changed, due in no small part to the research of Prof. Michal Schwartz of the Weizmann Institute of Science’s Department of Neurobiology.
“My assumption was always that the immune system does help repair the brain, but that it has a very unique way of communicating across the blood-brain barrier,” she says. “This assumption turned out to be correct. However, the work that it took to get there was very difficult.”
https://www.weizmann-usa.org/news-media/news-releases/same-microbe-different-effect/
Mar 27, 2019...
Seemingly identical bacteria may harbor genetic differences that affect the host-microbiome relationship
REHOVOT, ISRAEL—March 27, 2019—Our gut microbiome – the complement of bacteria we carry around in our intestines – has been linked to everything from obesity and diabetes to heart disease and even neurological disorders and cancer. In recent years, researchers have been sorting through the multiple bacterial species that populate the microbiome, asking which of them can be implicated in specific disorders. But a paper recently published in Nature addressed a new question: “What if the same microbe is different in different people?”
https://www.weizmann-usa.org/news-media/in-the-news/the-secret-social-lives-of-viruses/
Jun 18, 2019...
Illustration by Karol Banach
Geneticist Rotem Sorek could see that his bacteria were sick — so far, so good. He had deliberately infected them with a virus to test whether each ailing microbe soldiered on alone or communicated with its allies to fight the attack.
But when he and his team at the Weizmann Institute of Science in Rehovot, Israel, looked into the contents of their flasks, they saw something completely unexpected: the bacteria were silent, and it was the viruses that were chattering away, passing notes to each other in a molecular language only they could understand. They were deciding together when to lie low in the host cell and when to replicate and burst out, in search of new victims.
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