About Us
Founded in 1944, the American Committee for the Weizmann Institute of Science develops philanthropic support for the Weizmann Institute in Israel, and advances its mission of science for the future of humanity.
https://www.weizmann-usa.org/news-media/news-releases/the-triple-threat-of-coronavirus/
May 12, 2021... REHOVOT, ISRAEL—May 12, 2021—Severe symptoms of COVID-19, leading often to death, are thought to result from the patient’s own acute immune response rather than from damage inflicted directly by the virus. Intensive research efforts are therefore seeking to determine how the SARS-CoV-2 virus manages to mount an effective invasion while throwing the immune system off course. A new study, published in Nature, reveals a multipronged strategy that the virus employs to ensure its quick and efficient replication, while avoiding detection by the immune system. The study, conducted jointly by the research groups of Dr. Noam Stern-Ginossar at the Weizmann Institute of Science and Dr. Nir Paran and Dr. Tomer Israely of the Israel Institute for Biological, Chemical and Environmental Sciences, focused on understanding the molecular mechanisms at work during infection by SARS-CoV-2 at the cellular level.
May 12, 2021...
COVID-19 is so dangerous because the virus uses a three-pronged attack mechanism to stop cells from quickly triggering the immune system, Israeli scientists have concluded.
They offer a portrait of how exactly the SARS-CoV-2 virus behaves once inside human cells — they say it’s the most detailed to date — in an article published on Wednesday in the peer-reviewed journal Nature.
After hundreds of hours in their labs monitoring the virus interacting with cells, they have concluded that the virus mounts a hostile takeover on the cell’s protein-making machinery, and stops it from making proteins needed to galvanize the immune system.
https://www.weizmann-usa.org/news-media/news-releases/a-natural-food-supplement-may-relieve-anxiety/
May 18, 2021... REHOVOT, ISRAEL—May 18, 2021—A natural food supplement reduces anxiety in mice, according to a new Weizmann Institute of Science study. The plant-derived substance, beta-sitosterol, was found to produce the calming effect both on its own and in synergic combination with a common antidepressant, fluoxetine (brand name Prozac). If these findings, published in Cell Reports Medicine, are confirmed in clinical trials, they could point the way toward the use of beta-sitosterol as a treatment for relieving anxiety in humans.
https://www.weizmann-usa.org/news-media/video-gallery/decoding-the-functions-of-long-non-coding-rna/
Dec 22, 2021... Prof. Ulitsky’s discoveries have unlocked the potential of using lncRNAs as both therapeutic agents and targets with promising potential treatment of diseases such as cancer, brain injury, and epilepsy.
https://www.weizmann-usa.org/news-media/feature-stories/the-primordial-soap/
Mar 14, 2022...
What is the origin of life? It’s one of humanity’s greatest questions, and theories differ amidst the scientific community. Right now, the leading hypothesis is that life developed from RNA molecules, known for being able to self-replicate.
Weizmann’s Prof. Doron Lancet disagrees, and thinks it’s highly improbable that the origin of life traces back to a single complex molecule. More likely, he believes it traces back to assemblies of simple chemical compounds that can form spontaneously and reproduce as a whole, and he’s built a computational chemistry model to show the feasibility of this alternative timeline.
Aug 01, 2022... REHOVOT, ISRAEL—August 1, 2022— An egg meets a sperm – that’s a necessary first step in life’s beginnings, and it’s also a common first step in embryonic development research. But in a Weizmann Institute of Science study published today in Cell, researchers have grown synthetic embryo models of mice outside the womb by starting solely with stem cells cultured in a petri dish – that is, without the use of fertilized eggs. The method opens new horizons for studying how stem cells form various organs in the developing embryo, and may one day make it possible to grow tissues and organs for transplantation using synthetic embryo models.
https://www.weizmann-usa.org/news-media/feature-stories/maya-schuldiner-connecting-organelles/
Feb 15, 2022... Prof. Maya Schuldiner of Weizmann’s Department of Molecular Genetics studies how cells function, which in turn can help understand disease – particularly, rare diseases.In the end, it’s all about making a connection. In their recent study, Prof. Maya Schuldiner and her team from the Weizmann Institute of Science’s Molecular Genetics Department uncover for the first time how the cell’s Most Valuable Players – the nucleus and mitochondria – communicate through the formation of dedicated contact sites. Being able to tune in on these correspondences will allow scientists to better understand conditions where they are disrupted from cancer to neurodegenerative diseases. These findings join a series of recent discoveries in the budding field of contact site biology, some of which were made in Schuldiner’s lab.
Jan 25, 2023...
Researchers have for years tried to discover what determines “resilience to stress,” a term describing the ability to adapt to difficult situations and to overcome adversity. Is it acquired through experience, or is there a tendency to easily recover from stress possibly ingrained in us from a very early age or even from birth?
A new study lead by Prof. Gil Levkowitz of the molecular cell biology and molecular neuroscience departments at the Weizmann Institute of Science in Rehovot has revealed an important piece of this puzzle. The study examined zebrafish – small, black-and-white-striped, transparent fish whose natural habitat spans rivers, ponds and rice paddies in Pakistan, Myanmar, Nepal and India.
https://www.weizmann-usa.org/news-media/news-releases/plant-research-reaches-a-new-high/
Apr 30, 2023... REHOVOT, ISRAEL—May 1, 2023—A South African plant called a woolly umbrella is completely unrelated to the cannabis plant, yet it makes a slew of the active compounds found in cannabis – cannabinoids – including some that may have new medical uses. In a study published today in Nature Plants, Weizmann Institute of Science researchers identified more than 40 cannabinoids in the woolly umbrella, and they revealed the series of biochemical steps the plant takes when it makes these compounds. The researchers also showed how these steps can be reproduced in the lab to synthesize or even engineer new cannabinoids.
Aug 07, 2023...
REHOVOT, ISRAEL — August 8, 2023—Nonsmokers who develop lung cancer can be treated effectively with new drugs, but their tumors refuse to surrender without a fight. The drugs stop working in the long term because the tumors acquire secondary mutations that allow them to evade the medications’ therapeutic effect.
In research published today in the journal Cell Reports Medicine, investigators from the Weizmann Institute of Science report findings that may lead to relapse-free treatment for a sizeable subgroup of lung cancer patients. In a study in mice, scientists identified a biomarker that may help physicians treat select lung cancer patients with a single antibody-based drug that is likely to bring about full remission, without cancer relapse.