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Showing results 51-59 of 59 for 'Bacteria'


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    How Bacteria Hinder Chemotherapy

    To the list of reasons that chemotherapy sometimes does not work, we can now add one more: bacteria. In a study just published in Science, researchers describe their findings showing that certain bacteria can be found inside human pancreatic tumors. The findings further revealed that some of these bacteria contain an enzyme that inactivates a common drug used to treat various cancers, including pancreatic cancer. Working with mouse models of cancer, the scientists demonstrated how treatment with antibiotics on top of chemotherapy may be significantly superior to treatment with chemotherapy alone.

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    Bacteria Alert by Scientist

    The Israeli crystallographer, who shared the chemistry Nobel with Venkatraman Ramakrishnan and Thomas A. Steitz in 2009 for her work on ribosome, was delivering the 79th Foundation Day lecture on “Next Generation Environmental Friendly Antibiotics” at Bose Institute on Thursday. “Resistance to antibiotics is a real big problem to modern medicine. Multi-drug resistance has developed not because we use antibiotics, but because bacteria has evolved and uses mechanisms against other bacteria in their fight for resources,” Yonath said.

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    Bacterial Immune Systems Take the Stage

    Until a decade ago, scientists were not aware that bacteria had complex immune systems – ones that could keep up with the pace of evolution in viruses called phages that infect bacteria. That changed with the discovery of what is now the most famous bacterial immune mechanism: CRISPR. Scientists realized that CRISPR is a natural gene editor, and it has revolutionized the world of biological research in thousands of labs around the world. Researchers now understand that most microorganisms have sophisticated immune systems, of which CRISPR is just one element, but there has been no good way to identify these systems.

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    Researchers Discover 10 New Immune Systems in Bacteria

    Bacteria have been defending themselves from phages—viruses that attack bacterial cells—for billions of years, and unlocking the immune mechanisms they use to protect themselves has led to the development of powerful molecular biology tools such as restriction enzymes and CRISPR-Cas9. Now, researchers report in Science today (January 25) that they have discovered 10 more immune systems that bacteria use to protect themselves against phages and plasmids, opening up the possibility to add new tools to the molecular biology toolbox.

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    Environment, Not Genetics, Primarily Shapes Microbiome Composition

    Environment plays a much greater role than host genetics in determining the composition of the human gut microbiome, according to a study published today (February 28) in Nature. And including microbiome characteristics when predicting people’s traits, such as cholesterol levels or obesity, makes those estimates more accurate than only personal history, such as diet, age, gender, and quality of life, the study finds.

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    Bacterial Immune Systems Take the Stage

    Until a decade ago, scientists were not aware that bacteria had complex immune systems that could keep up with the pace of evolution in viruses called phages that infect bacteria. That changed with the discovery of what is now the most famous bacterial immune mechanism: CRISPR. This is a natural gene editor that has revolutionized the world of biological research in thousands of labs around the world. Researchers now understand that most microorganisms have sophisticated immune systems of which CRISPR is just one element; but there has been no good way to identify these systems.

    /news-media/in-the-news/bacterial-immune-systems-take-the-stage
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    200 Teens in Israel and Massachusetts Run Superbug Tests

    The 6,000 miles between them made no difference when 200 students in Israel and in the Boston area jointly created evolution in test tubes. The 10-day science experiment helped them understand how antibiotic-resistant bacterial “superbugs” evolve. The teens designed their experiments on Google Sheets, and these instructions were automatically carried out by a robot in a lab at the University of Massachusetts.

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