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5 results for Personalized medicine

A New Approach to Tailoring Cancer Therapy: Tapping Into Signaling Activities in Cancer Cells
A New Approach to Tailoring Cancer Therapy: Tapping Into Signaling Activities in Cancer Cells

https://www.weizmann-usa.org/news-media/news-releases/a-new-approach-to-tailoring-cancer-therapy-tapping-into-signaling-activities-in-cancer-cells/

Jul 16, 2020... REHOVOT, ISRAEL—July 16, 2020—Choosing the right drug for each cancer patient is key to successful treatment, but physicians currently have few reliable pointers to guide them in designing treatment protocols. Researchers at the Weizmann Institute of Science and the Broad Institute of MIT and Harvard have now developed a new method for selecting the best drug therapy for a given tumor, based on assigning scores to the cells’ internal messaging activities. In addition to helping physicians choose from a list of existing treatments, the method can help identify new molecular targets for the development of future drugs. In fact, the researchers have already used it to single out a gene that can be targeted for effectively treating breast cancers with a BRCA mutation. The study was recently published in Nature Communications.

TAGS: Genetics, Cancer, Biology, Cancer treatment, Personalized medicine

Weizmann Study Identifies Genes Connected to Myeloma Drug Resistance
Weizmann Study Identifies Genes Connected to Myeloma Drug Resistance

https://www.weizmann-usa.org/news-media/in-the-news/weizmann-study-identifies-genes-connected-to-myeloma-drug-resistance/

Feb 28, 2021... Researchers from the Weizmann Institute of Science and the Tel Aviv Sourasky Medical Center have found 30 genes that seem to be responsible for the resistance that multiple myeloma shows to treatment, which may help lead to more informed, personalized treatment for patients.
Malignant myeloma is a cancer of the antibody-producing plasma cells in bone marrow. Most patients develop resistance to medications and in some, the cancer is resistant to therapy from the start.

TAGS: Genetics, Cancer treatment, Personalized medicine

May is Melanoma/Skin Cancer Detection and Prevention Month
May is Melanoma/Skin Cancer Detection and Prevention Month

https://www.weizmann-usa.org/news-media/feature-stories/may-is-melanoma-skin-cancer-detection-and-prevention-month-1/

May 14, 2021... This summer, after more than a year of pandemic shutdowns, we are more excited than ever to get outside. But we can’t let down our guard when it comes to sun exposure, which is the primary cause of the most common cancer in the world: skin cancer. In fact, the Skin Cancer Foundation says that over 85% of melanomas are linked to UV radiation, and having more than five sunburns doubles your risk of developing this deadliest form of skin cancer.

TAGS: Cancer, Bacteria, Personalized medicine

The Viruses That Fight Disease: A Surprising Precision Weapon against Crohn’s and Ulcerative Colitis
The Viruses That Fight Disease: A Surprising Precision Weapon against Crohn’s and Ulcerative Colitis

https://www.weizmann-usa.org/news-media/news-releases/the-viruses-that-fight-disease-a-surprising-precision-weapon-against-crohn-s-and-ulcerative-colitis/

Aug 04, 2022... REHOVOT, ISRAEL—August 4, 2022—The myriads of microbes in our gut, collectively termed the microbiome, are considered important to our health, but they can also harbor bacteria that contribute to inflammatory bowel disease or other disorders. Currently, however, it is impossible to target such disease-contributing bacteria without harming the surrounding beneficial microbes. Antibiotics kill friendly microbes along with the harmful ones, and in any event, they tend to trigger bacterial resistance and to have side effects. In a study published today in Cell, Weizmann Institute of Science researchers have demonstrated the feasibility of a potential therapy for killing inflammation-causing gut bacteria in a targeted manner: by using viruses that infect them.

TAGS: Medicine, Bacteria, Virus, Inflammation, Clinical trials, Personalized medicine, Microbiome, Immunology

Putting Liquid Biopsies on Solid Ground: Cancer Diagnosis from a Milliliter of Blood 
Putting Liquid Biopsies on Solid Ground: Cancer Diagnosis from a Milliliter of Blood 

https://www.weizmann-usa.org/news-media/news-releases/putting-liquid-biopsies-on-solid-ground-cancer-diagnosis-from-a-milliliter-of-blood/

Sep 08, 2022... REHOVOT, ISRAEL—September 8, 2022—Blood tests – simple, noninvasive and economically feasible – promise to become the next major milestone in cancer diagnosis. However, most of these tests, dubbed liquid biopsies, are currently not reliable enough for widespread use. A new, multiparameter approach developed at the Weizmann Institute of Science may lead to a blood test that will diagnose cancer with unprecedented accuracy. This research is being published today in Nature Biotechnology.

TAGS: Cancer, Blood, Personalized medicine, Artificial intelligence, Molecular cell biology

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